Skip to main content
All labs

Biology · BIO-019

Evidence of Common Ancestry

Compare arm bones, embryos, and DNA from five animals. Build the family tree.

  • NGSS HS-LS4-1
  • AP Biology Unit 7
  • AP Biology Investigation 3
Start free

Included with a subscription. Create a free account to get started.

Members

About this lab

Inspect vertebrate limb structures and molecular sequences and arrange a tree from the combined evidence. In this interactive 3D investigation for high school students, switch between the bone, developmental-source, and protein views, reveal internal structures, and compare corresponding positions before placing the species on branches. Bone groups and sequence-difference counts supply independent comparisons across the displayed animals. Developmental material retains its source and stage labels, including limits where information is incomplete. A protein close-up adds cellular context to the molecular record, while the tree station brings the selected evidence into a proposed relationship pattern. The experiment is aligned with NGSS HS-LS4-1, AP Biology Unit 7, and AP Biology Investigation 3.

What this investigation asks

Different lines of evidence can support a hypothesis of common ancestry without producing identical-looking structures in every descendant. This investigation compares forelimb organization, developmental sequences, molecular differences, and branching diagrams. Begin by specifying which feature is being compared and what similarity means in that context. A shared function can evolve in different structures, while homologous structures can acquire different functions. The goal is to evaluate relationships through a connected evidence set rather than assuming that the most similar outward appearance necessarily identifies the closest relationship for every comparison.

Design and measure the comparison

Compare corresponding anatomical structures using a consistent basis, then distinguish homologous from analogous features. Follow the appearance and disappearance of selected embryonic structures in the course timeline instead of interpreting one isolated developmental image as a complete adult form. For the molecular comparison, align corresponding sequence positions and count differences under the stated method. Retain the selected protein and sequence length. A mismatch count drawn from unequal or unaligned regions does not answer the same relationship question as a count across the listed homologous mature sequences in this activity.

Connect the record to the model

Use shared derived characters and the supplied molecular comparisons to construct a branching hypothesis. Identify the outgroup and explain what a node represents. Branching order describes inferred shared ancestry; it does not rank living species from less evolved to more evolved. Compare the evidence supporting each grouping and inspect where different data may leave an alternative unresolved. Molecular differences can inform relative relationships in the teaching model, but an uncalibrated count is not automatically an exact elapsed-time measurement. The number of displayed branches also does not establish that every extinct lineage has been sampled.

Interpret the evidence and its limits

Keep the selected evidence and its limitations visible when revising a tree. A result can favor one relationship over another without making the diagram immutable. Similarity due to common ancestry and similarity due to convergent function require different explanations. The developmental model illustrates particular features and sequences, not a claim that an embryo literally passes through the complete adult forms of ancestral species. A final argument should identify the anatomical, developmental, or molecular evidence for each inference and describe which additional observation would discriminate between plausible competing branching hypotheses.

Reference conditions and quantities

The course's molecular reference set contains five mature sequences of 104 positions each. Equal listed lengths make the specified position-by-position comparison well defined, but the mismatch count still requires the sequence identities and alignment. This is a reference-data scope statement, not an estimate of evolutionary time or a claim that every protein in those organisms has the same length.

Use the record to test your explanation

Write a prediction before collecting the comparison, naming the quantity that should change and the condition you will alter. Keep a reference run and vary one factor at a time when the question calls for a controlled test. Record the selected apparatus settings, units, and measurement interval. Where an activity supplies Ideal and Real modes or seeded variation, retain that identity with each record rather than mixing incompatible runs in one calculation.

Separate an instrument reading or counted observation from the model relationship used to explain it. Keep raw values alongside derived results so another student can reconstruct the argument. A graph needs labeled axes and a stated comparison range. If a result differs from a reference, inspect the conditions, rounding, and measurement procedure before changing the explanation.

For a classroom discussion, compare claims supported by the same evidence and identify an additional measurement that would distinguish competing accounts. Finish with a claim, the relevant observations, and reasoning tied to this course's model. State a specific limitation instead of assigning a general error label to every disagreement.

Inspect inheritance variation in Mendelian Genetics, then compare selective mechanisms in Natural Selection. Separate evidence for a historical relationship from the processes that can change trait or allele distributions in a modeled population.

Common questions

Standards alignment

  • NGSS HS-LS4-1
  • AP Biology Unit 7
  • AP Biology Investigation 3